Vaishali Kumar, MBBS, Sarcoma Oncology Research Center, Santa Monica, CA, discusses findings from an analysis of CCNG1 expression in 137 patients across various cancer types treated with DRG-101, a tumor-targeted retrovector. All tumors exhibited enhanced CCNG1 expression, with varying levels across patients. Notably, patients with sustained remission from metastatic pancreatic cancer and breast cancer showed specific CCNG1 expression levels. DRG-101 additionally has potential in combination therapy for advanced pancreatic cancer, sarcoma, and breast carcinoma. This interview took place at American Association for Cancer Research (AACR) Annual Meeting 2024 in San Diego, CA.
Interview with Sarcoma Experts Robin L Jones, MD & Sant P Chawla, MD
Robin L Jones, MD - Royal Marsden Hospital, London, UK; Sant P Chawla, MD - Sarcoma Oncology Center, California, USA
PRESS RELEASE: DeltaRex-G for CAR-T Cell Therapy Induced Cytokine Release Syndrome
INTERVIEW: American Society of Gene & Cell Therapy (ASGCT) 27th Annual Meeting
ANNOUNCEMENT: BostonGene’s Identification of Elevated CCNG1 Levels in Multiple Cancer Types Unlocks Potential of Tumor-Targeted Gene Therapy
ANNOUNCEMENT: Aveni Foundation Publishes "From Mendel to Gene Therapy" Mapping the History of Genetic Medicine
The Aveni Foundation and the Cancer Center of Southern California proudly announce the publication of “From Mendel to Gene Therapy” by Jeffrey S, Brigham DA, Chawla SP, Federman N, Hall FL and Gordon EM (Anticancer Res.43:4257-4261, 2023). In this article, Jeffrey et al. map out the history of genetic medicine from Gregor Mendel, whose experimentation in the field of heredity laid the groundwork for modern genetics, consequently paving the way for gene therapy.
Illustration of the chronology of events from Gregor Mendel’s experiments on pea plants to the discovery of the genetic code to genetic engineering of viral vectors for gene therapy applications.
PRESS RELEASE: A Novel Biomarker For DeltaRex-G CCNG-1 Inhibitor Therapy
Dr. Chawla - 9/30/23
Dr. Sant Chawla of Cancer Center of Southern California speaks about his clinical experience with DeltaRex-G (formerly: Rexin-G) at Aveni Foundation’s “An Evening with Gustavo Santaolalla” on September 30, 2023.
Kendra Krause & Ruth Oliver - 9/30/23
Message from the President: An Evening with Gustavo Santaolalla
On behalf of Aveni Foundation and our Board of Directors, I would like to thank all who attended Aveni Foundation’s private event, “An Evening with Gustavo Santaolalla,” and who contributed their talents and resources in celebration, in tribute, and in support of our mission: Broadly, to expedite the development of gene-targeted technologies for cancer and Parkinson’s disease, and specifically, to resurrect DeltaRex-G for the benefit of cancer patients worldwide. Special acknowledgment must be extended to Gustavo and his gifted team of musicians and engineers for a unique and memorable performance; to Dr. Sant and Kusum Chawla for welcoming us to their beautiful Beverly Hills home and providing delicious Indian cuisine; and to our Emcees Sara Welch and Honorable Marc Aveni for setting such an engaging tone for the evening. With gratitude to our sponsors: BostonGene Corp., Immix Biopharma, Zouk Capital, Expression Therapeutics, Delta Next-Gene, and Counterpoint Biomedica; to Telefora for providing the sparkling flower bouquets; to Trader Joes for providing beverages; to Fender for donating two guitars; to Isidric Panganiban’s team (photography & videography), Barbara Hollander (silent auctioneer), Marty Berwitt (event advisor); and last but not least, to our event planners: Dr. Chet Bohac, Mark Nguyen, Mia Radcliffe, and Kevin Winston, for such an outstanding and seamless execution! Together, we made this event a success!
- Dr. Erlinda M Gordon
Happening Soon!
PRESS RELEASE: USFDA Authorizes DeltaRex-G as Platform Therapy
SAVE THE DATE: Gustavo Santaolalla Performs a Unique Solo Presentation for Aveni Foundation
SAVE THE DATE: SEPTEMBER 30, 2023 Beverly Hills, California
Gustavo Santaolalla, is recognized as one of the most highly acclaimed and prolific contemporary Argentine musicians in the world. Santaolalla has produced more than 100 albums by some of Latin-America’s most relevant alternative musicians, including Café Tacvba, Julieta Venegas, Bajofondo, Los Tigres del Norte and Juanes and has won 2 Grammys and 19 Latin Grammys. He has composed film scores for Alejandro González Iñárritu’s Amores Perros, 21 Grams, Babel and Biutiful, Walter Salles’ Motorcycle Diaries and On the Road, and Ang Lee’s Brokeback Mountain, for which he received his first Oscar for Best Original Score and a Golden Globe for Best Original Song, “A Love That Will Never Grow Old” co-written with Bernie Taupin. The following year, Santaolalla received his second Oscar for Best Original Score for Babel. Santaolalla also created the music for Sony Playstation and Neil Druckmann’s multi-award winning The Last of Us and most recently scored the HBO series based on the beloved videogame.
PRESS RELEASE: Working Toward a Cure for Advanced Sarcoma
ANNOUNCEMENT: Gene-Targeted Diagnostics and Therapies for Cancer | Frontiers Research Topic
Celebrating the 200th Mendel’s Anniversary: Gene-Targeted Diagnostics and Therapies for Cancer | Frontiers Research Topic
ANNOUNCEMENT: Two Year Results of Blessed Protocol Expanded Access for DeltaRex-G
Presented at the American Society of Gene and Cell Therapy Annual Meetings in Washington DC, May 18, 2022